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Lalremsanga, H. T.
- Some Phytochemical, Antimicrobial and Anticancer Tests for an Aqueous extract of Acmella oleracea
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Affiliations
1 Department of Life Sciences, Pachhunga University College, Aizawl 796001, Mizoram, IN
2 Department of Pharmacy, Regional Institute of Paramedical and Nursing Sciences, Zemabawk 796017, Mizoram, IN
3 Department of Zoology, Mizoram University, Tanhril 796004, Mizoram, IN
1 Department of Life Sciences, Pachhunga University College, Aizawl 796001, Mizoram, IN
2 Department of Pharmacy, Regional Institute of Paramedical and Nursing Sciences, Zemabawk 796017, Mizoram, IN
3 Department of Zoology, Mizoram University, Tanhril 796004, Mizoram, IN
Source
Research Journal of Pharmacy and Technology, Vol 12, No 6 (2019), Pagination: 3033-3037Abstract
Acmella oleracea (family Asteraceae) is known for its diverse applications such as food supplement, vegetable, antioxidant, antineoplastic, antimicrobial, ornamental plant and pig fodder. We prepared an aqueous extract from which the presence of alkaloids, tannins and saponins were detected. These chemical groups have been known for their wide-ranging therapeutic properties. The antibacterial activity was tested on Gram-negative bacteria such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Escherichia coli, and a Gram-positive species Bacillus subtilis. The plant extract showed no activity compared to that of the standard antibiotic tetracycline. Cytotoxic activity was also studied on cancer cell lines. We found an inverse relationship between treatment concentration and percent inhibition for HeLa (ATCC® CCL-2™) and V79 (ATCC® CCL-93™), however, the plant extract showed negligible effect on Dalton’s lymphoma ascites even at the highest concentration tested. The lower degree of inhibitions observed at higher concentrations for HeLa and V79 suggests that the plant extract might confer proliferative effect rather than antimitogenic effects on the cancer cells. The results indicate that A. oleracea has unique medicinal properties, which in turn provide the rationale for further investigations.Keywords
Acmella oleracea, Medicinal Plant, Antibacterial, Cytotoxicity, Cancer Cells.
References
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- Unveiling the Unexplored and Critically Endangered Ilex khasiana for its Antioxidant Properties
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Authors
Charles Lalnunfela
1,
H. T. Lalremsanga
1,
T. C Lalhriatpuii
2,
David Lalnunzira
2,
K. Lalchhandama
3
Affiliations
1 Department of Zoology, Mizoram University, Tanhril – 796004, Mizoram, IN
2 Department of Pharmacy, Regional Institute of Paramedical and Nursing Sciences, Zemabawk – 796017, Mizoram, IN
3 Department of Life Sciences, Pachhunga University College, Aizawl – 796001, Mizoram, IN
1 Department of Zoology, Mizoram University, Tanhril – 796004, Mizoram, IN
2 Department of Pharmacy, Regional Institute of Paramedical and Nursing Sciences, Zemabawk – 796017, Mizoram, IN
3 Department of Life Sciences, Pachhunga University College, Aizawl – 796001, Mizoram, IN
Source
Journal of Natural Remedies, Vol 19, No 4 (2019), Pagination: 214-220Abstract
Ilex khasiana Purk. is an evergreen tree of Aquifoliaceae family reportedly endemic to Khasi Hills, Meghalaya, India; but it is also seen in a localised area of Aizawl, Mizoram, India. There is a vast history about the genus Ilex with reference to their medicinal uses in different traditional practices such as, in the treatment of coronary heart diseases, hypertension, hyperlipemia and hepatitis. Interestingly, I. khasiana is relatively unknown and yet it is known to possess multiple medicinal characteristics. The antioxidant potential studies were conducted on leaf extract specimens from Mizoram, using petroleum ether (IKP), chloroform (IKC) and methanol (IKM). IKM had the highest total antioxidant activity with 76.42 ascorbic acid equivalent (AE) mg/g, followed by IKP with 44.27 AE mg/g, and then by IKC with 17.08 AE mg/g respectively. The reducing power assay showed a concentration-dependent activity against potassium ferricyanide. The total phenolic content was found to be 3.46 gallic acid equivalent (GAE) mg/g for IKM and 1.450 GAE mg/g for IKC respectively. The total flavonoid content was 41.9 quercetin equivalent (QE) mg/g for IKC and 30.8 QE mg/g for IKM. IKP did not show any activity in phenolic and total flavonoid assays.Keywords
Antioxidant Activity, Flavonoids, Ilex khasiana, Phenolics, Reducing Power.Full Text
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- Community-based approaches for wildlife conservation and livelihood options: a case study from Dampa Tiger Reserve, Mizoram, India
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Authors
Affiliations
1 Department of Zoology, Mizoram University, Tanhril 796 004, India
1 Department of Zoology, Mizoram University, Tanhril 796 004, India
Source
Current Science, Vol 121, No 7 (2021), Pagination: 886-890Abstract
No Abstract.Full Text
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